Population
Single glycerinated skeletal muscle fibers with fluorescent-labeled myosin cross-bridges
Comparison
Time-resolved fluorescence polarization… vs Relaxed versus rigor states under different…
Design
Preclinical
Authors
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Animal skeletal muscle data only; leaves open applicability to human cardiac myosin dynamics in health or disease.
This basic science study characterizes the rotational motions of myosin cross-bridges in skeletal muscle fibers, demonstrating distinct rotational correlation times depending on the muscle state and measurement axis.
Burghardt et al. (1985) studied this question.
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