Population
Skeletal muscle myofibrils and synthetic thick filaments labeled with eosin-maleimide
Comparison
5 mM MgATP vs Rigor (no ATP)
Design
Preclinical
Authors
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No immediate clinical implications; hypothesis-generating for cross-bridge dynamics in animal models.
This study provides the first time-resolved measurements under physiological conditions demonstrating that MgATP induces complex microsecond rotational motions in muscle cross-bridges.
Ludescher et al. (1988) studied this question.
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