A serial 3- and 9-year optical coherence tomography assessment of vascular healing response to sirolimus- and paclitaxel-eluting stents

22 patients with stable coronary artery disease (SCAD) who underwent elective PCI with single early-generation DES (sirolimus-eluting or paclitaxel-eluting stents) and had at least 36 months of uneventful follow-up. Mean age ~61, ~72% male. Key inclusion: stent 2.5-3.5 mm in diameter, adherent to DAPT for 12 months. Key exclusion: history of target vessel revascularization (TVR), MI, or stroke between index PCI and planned OCT; left main culprit, lesions <10 mm from ostium, CTO, eGFR <30 mL/min/1.73 m2.

Implantation of early-generation sirolimus-eluting stents (SES) or paclitaxel-eluting stents (PES) with serial optical coherence tomography (OCT) assessment at 3 and 9 years post-procedure.

Comparison of intra-individual OCT findings between 3-year and 9-year follow-up, as well as comparison between SES and PES groups.

Change in the neointimal thickness evaluated by OCT between 3 and 9 years of follow-up.surrogate