Why the study?
Does genetic variability of the ET-1 gene affect the progression of blood pressure and left ventricular mass in multiethnic youth?
Population
537 European American and black youths
Comparison
Genetic variability of the ET-1 gene vs Noncarriers or individuals with different…
Design
Cohort
Follow-up
15 years
Authors
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ET-1 variants may affect SBP and LVM in youth; hypothesis-generating, needs replication before any clinical use.
Does genetic variability of the ET-1 gene affect the progression of blood pressure and left ventricular mass in multiethnic youth?
Genetic variations in the ET-1 gene have sex-specific effects on blood pressure progression and socioeconomic status-specific effects on left ventricular mass in multiethnic youth.
Dong et al. (2004) studied this question.
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