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February 1, 1995Journal of Clinical MicrobiologyOpen Access

Use of solid-phase immune electron microscopy for classification of Norwalk-like viruses into six antigenic groups from 10 outbreaks of gastroenteritis in the United States

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Population

Fecal specimens from 10 outbreaks of gastroenteritis investigated in the United States between 1987 and 1992

Design

Other

Authors

DLD. C. LewisUniversity of BristolTATamie AndoCenters for Disease Control and PreventionCHCharles D. HumphreyCenters for Disease Control and Prevention

Discussion

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Overview

May inform norovirus outbreak diagnostics; leaves open validation and clinical impact in prospective studies.

Structured PICO

P
Population
Fecal specimens from 10 outbreaks of gastroenteritis investigated in the United States between 1987 and 1992
I
Intervention
Solid-phase immune electron microscopy
O
Outcome
Classification into antigenic groups

Solid-phase immune electron microscopy identified greater antigenic diversity among Norwalk-like viruses than previously recognized, classifying them into six groups.

Cite This Study

Lewis et al. (1995) studied this question.

synapsesocial.com/papers/6a6faf2f5d37378ac1dcbdcehttps://doi.org/10.1128/jcm.33.2.501-504.1995
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Genomic diversity of small round structured viruses in the United Kingdom1994 · 65 citations
  2. 2Characterization of a variant strain of Norwalk virus from a food-borne outbreak of gastroenteritis on a cruise ship in Hawaii1994 · 82 citations
  3. 3Sequence and Genome Organization of a Human Small Round-Structured (Norwalk-Like) Virus1993 · 380 citations
  4. 4Three serotypes of norwalk‐like virus demonstrated by solid‐phase immune electron microscopy1990 · 72 citations
  5. 5Visualization by Immune Electron Microscopy of a 27-nm Particle Associated with Acute Infectious Nonbacterial Gastroenteritis1972 · 1,134 citations