Population
Normotensive rats fed low-salt (0.45%) or high-salt (7%) diets
Comparison
Pharmacological blockade with ANG II-receptor… vs Baseline response to microvascular pressure…
Design
Preclinical
Authors
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High-salt diets may blunt myogenic arteriolar tone via ANG II; hypothesis-generating for human microvascular studies.
High dietary salt intake attenuates arteriolar myogenic responsiveness in striated muscle by decreasing circulating angiotensin II and increasing local kinin levels.
Nurkiewicz et al. (2000) studied this question.
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