March 1, 1993Journal of Clinical MicrobiologyOpen Access

Serologic analysis of human rotavirus serotypes P1A and P2 by using monoclonal antibodies

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Population

Human rotavirus (HRV) VP4 serotypes P1A (strain Wa) and P2 (strain ST3)

Design

Preclinical

Authors

LPLuis Padilla-NoriegaUniversidad Nacional Autónoma de México RWR Werner-EckertVA Palo Alto Health Care System EMErich R. MackowStony Brook School

Discussion

Member takes

Implication

May enable serotype-specific HRV tools; leaves open human translation from animal models.

Structured PICO

Population

Human rotavirus (HRV) VP4 serotypes P1A (strain Wa) and P2 (strain ST3)

Intervention

13 VP4-specific neutralizing monoclonal antibodies (NMAbs)

Outcome

Reactivity and serotypic specificity by neutralization assay and ELISAsurrogate

The study identifies specific neutralizing monoclonal antibodies that can distinguish between human rotavirus serotypes P1A and P2, including a novel epitope.

Cite This Study

Padilla-Noriega et al. (1993) studied this question.

synapsesocial.com/papers/6a6fb0e1febe604dd7088dc4 https://doi.org/10.1128/jcm.31.3.622-628.1993

View Full Paper

Ask AI

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Serologic analysis of human rotavirus serotypes P1A and P2 by using monoclonal antibodies

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Serologic analysis of human rotavirus serotypes P1A and P2 by using monoclonal antibodies

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider