Why the study?
Does human rotavirus infection in adults primarily stimulate neutralizing antibodies against the VP3 or VP7 protein?
Population
Adult subjects infected with the CJN strain of human rotavirus
Design
Other
Authors
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Supports VP3 as dominant neutralizing target in adult rotavirus infection; leaves open implications for vaccine antigen selection.
Does human rotavirus infection in adults primarily stimulate neutralizing antibodies against the VP3 or VP7 protein?
VP3, rather than VP7, appears to be the primary immunogen stimulating neutralizing antibodies during human rotavirus infection.
Ward et al. (1988) studied this question.
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