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November 1, 2002Journal of VirologyOpen Access

Frequent Reassortments May Explain the Genetic Heterogeneity of Rotaviruses: Analysis of Finnish Rotavirus Strains

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Population

Rotavirus isolates from 17 epidemic seasons (1980 through 1997) in Finland

Design

Other

Authors

LMLeena MaunulaCBCarl‐Henrik von Bonsdorff

Discussion

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Overview

Rotavirus surveillance should track reassortment; leaves open segment roles in strain emergence and vaccine performance.

Structured PICO

P
Population
Rotavirus isolates from 17 epidemic seasons (1980 through 1997) in Finland
I
Intervention
Nucleotide sequencing and phylogenetic analysis of 11 RNA segments
O
Outcome
Genetic diversity and phylogenetic clusters of RNA segments

Frequent genetic reassortment likely explains the extensive genetic diversity and number of electropherotypes among rotaviruses.

Cite This Study

Maunula et al. (2002) studied this question.

synapsesocial.com/papers/6a6fb38e439bab0cabc2e243https://doi.org/10.1128/jvi.76.23.11793-11800.2002
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Also Consider

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  5. 5Detection of Porcine Rotavirus Type G9 and of a Mixture of Types G1 and G5 Associated with Wa-Like VP4 Specificity: Evidence for Natural Human-Porcine Genetic Reassortment1999 · 78 citations