August 5, 2010The Journal of Infectious DiseasesOpen Access

Determination of the G and P Types of Previously Nontypeable Rotavirus Strains from the African Rotavirus Network, 1996–2004: Identification of Unusual G Types

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Population

215 nontypeable rotavirus samples collected from children <5 years of age by members of the African…

Design

Other

Authors

MEMathew D. EsonaSefako Makgatho Health Sciences University ASA. Duncan SteeleNational Health Laboratory Service TKTara KerinUniversity of California, Los Angeles

Discussion

Member takes

Implication

Rotavirus genotyping may need periodic primer updates; leaves open optimal reevaluation frequency for surveillance.

Structured PICO

Population

215 nontypeable rotavirus samples collected from children <5 years of age by members of the African Rotavirus Network

Intervention

Reverse-transcription polymerase chain reaction analysis and sequencing

Outcome

Identification of G and P types of previously nontypeable rotavirus strains

Nucleotide substitutions at primer binding sites can cause failure in rotavirus genotyping, highlighting the need for regular evaluation of genotyping methods.

Cite This Study

Esona et al. (2010) studied this question.

synapsesocial.com/papers/6a6fb0dffebe604dd7088dad https://doi.org/10.1086/653552

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Determination of the G and P Types of Previously Nontypeable Rotavirus Strains from the African Rotavirus Network, 1996–2004: Identification of Unusual G Types

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Determination of the G and P Types of Previously Nontypeable Rotavirus Strains from the African Rotavirus Network, 1996–2004: Identification of Unusual G Types

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider