February 1, 2001Microbiology and ImmunologyOpen Access

Molecular Characterization in the VP7, VP4 and NSP4 Genes of Human Rotavirus Serotype 4 (G4) Isolated in Japan and Kenya

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Population

12 isolates of human rotavirus serotype 4 and standard strains

Design

Preclinical

Authors

SKSatoshi KudoTokyo Institute of Technology YZYumei ZhouWannan Medical College XCXin‐Ru Cao

Discussion

Member takes

Implication

Supports G4 rotavirus genetic classification into three combinations; leaves open relevance for human surveillance and vaccines.

Structured PICO

Population

12 isolates of human rotavirus serotype 4 (G4) (nine from Japan and three from Kenya) and standard strains (Hochi, Odelia, ST3, VA70)

Intervention

Molecular characterization using reverse transcription polymerase chain reaction with subtype specific primers, restriction fragment length polymorphism analysis, and sequence analysis

Outcome

Intraserotypic variations in the VP7, VP4 and NSP4 genessurrogate

Human rotavirus serotype 4 (G4) isolates can be classified into three distinct genetic combinations based on VP7, VP4, and NSP4 gene analysis.

Cite This Study

Kudo et al. (2001) studied this question.

synapsesocial.com/papers/6a6fb45ff44fa9f079dd2d23 https://doi.org/10.1111/j.1348-0421.2001.tb01286.x

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Molecular Characterization in the VP7, VP4 and NSP4 Genes of Human Rotavirus Serotype 4 (G4) Isolated in Japan and Kenya

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Molecular Characterization in the VP7, VP4 and NSP4 Genes of Human Rotavirus Serotype 4 (G4) Isolated in Japan and Kenya

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider