Why the study?
Does blocking the Fas/FasL system with antibodies reduce myocardial injury in a rat model of autoimmune myocarditis?
Does blocking the Fas/FasL system with antibodies reduce myocardial injury in a rat model of autoimmune myocarditis?
The Fas/FasL system mediates apoptosis in autoimmune myocarditis, and its blockade reduces myocardial inflammation in a rat model.
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Fas/FasL blockade attenuates rat myocarditis; hypothesis-generating for human autoimmune disease, with no clinical implications yet.
Ishiyama et al. (1998) studied this question.
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