Why the study?
Despite extensive knowledge of the cardioprotective effects of estrogen, clinical studies in myocardial infarction and cardiovascular diseases still show both favorable and unfavorable profiles.
Does estrogen receptor modulation improve cardiac dysfunction after myocardial infarction?
Comparison
Estrogen receptor modulation and estradiol effects in myocardial infarction-induced cardiac dysfunction
Design
Review
Authors
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ER modulation may confer cardioprotection; leaves open targeted therapies pending clinical validation.
Does estrogen receptor modulation improve cardiac dysfunction after myocardial infarction?
Estrogen receptor modulation represents a potential therapeutic target for preventing cardiac dysfunction and adverse remodeling after myocardial infarction, though clinical studies have shown mixed results.
Silva et al. (2021) studied this question.
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