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January 1, 2014Methodist DeBakey Cardiovascular JournalOpen Access

A Contemporary Review on the Genetic Basis of Atrial Fibrillation

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Population

Individuals with atrial fibrillation

Design

Review

Authors

JRJason D. RobertsElectrophysiologyMGMichael H. GollobElectrophysiology

Discussion

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Overview

Genotype-based AF subtyping remains hypothesis-generating; leaves open whether it improves outcomes or guides therapy in prospective trials.

Structured PICO

P
Population
Individuals with atrial fibrillation

Understanding the genetic basis of atrial fibrillation could lead to genotype-guided pharmacogenetic treatment strategies with improved efficacy.

Cite This Study

Roberts et al. (2014) studied this question.

synapsesocial.com/papers/6a6fbcf75d37378ac1dccc70https://doi.org/10.14797/mdcj-10-1-18
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Evaluation of the role of IKAChin atrial fibrillation using a mouse knockout model2001 · 242 citations
  2. 2Evaluation of non-synonymous NPPA single nucleotide polymorphisms in atrial fibrillation2010 · 26 citations
  3. 3Impact of Atrial Fibrillation on the Risk of Death1998 · 4,612 citations
  4. 4Natriuretic Peptides: An Update on Bioactivity, Potential Therapeutic Use, and Implication in Cardiovascular Diseases2008 · 196 citations
  5. 5Validation of a New Simple Scale to Measure Symptoms in Atrial Fibrillation2009 · 180 citations