Why the study?
What is the incidence and extent of calcification in explanted glutaraldehyde-treated porcine prosthetic heart valves, and how is it affected by age and duration of implantation?
Population
73 patients (15 children, 58 adults) with 82 explanted glutaraldehyde-treated porcine prosthetic heart valves.
Design
Cohort
Follow-up
Average time implanted 4.6 +/- 1.7 years for children, 3.2…
Authors
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Calcification risk escalates with duration and younger age; may inform surveillance but leaves open optimal valve selection.
What is the incidence and extent of calcification in explanted glutaraldehyde-treated porcine prosthetic heart valves, and how is it affected by age and duration of implantation?
Calcification of porcine prosthetic heart valves is strongly accelerated in children and increases significantly with the duration of implantation in adults.
Cipriano et al. (1982) studied this question.
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