September 14, 2004Circulation
Relationship Between Cardiovascular Risk as Predicted by Established Risk Scores Versus Plaque Progression as Measured by Serial Intravascular Ultrasound in Left Main Coronary Arteries
Why the study?
Do established cardiovascular risk scores (PROCAM, SCORE, Framingham) correlate with plaque progression measured by serial IVUS in patients with established atherosclerosis?
Population
56 patients with established atherosclerosis in left main coronary arteries
Design
Cohort
Follow-up
18+/-9 months
Authors
Discussion
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Member takes
Implication
Risk scores may stratify progression risk in secondary prevention; extends validation to serial IVUS but leaves open therapeutic implications.
Structured PICO
Do established cardiovascular risk scores (PROCAM, SCORE, Framingham) correlate with plaque progression measured by serial IVUS in patients with established atherosclerosis?
P
Population
56 patients with established atherosclerosis in left main coronary arteries
I
Intervention
Cardiovascular risk estimation using PROCAM, SCORE, and Framingham risk scores
O
Outcome
Plaque progression and lumen reduction assessed with serial intravascular ultrasound (IVUS)surrogate
Established primary prevention risk scores (PROCAM, SCORE, Framingham) correlate linearly with plaque progression measured by serial IVUS in patients with established atherosclerosis.
Cite This Study
Birgelen et al. (2004) studied this question.