Why the study?
Is autoregulation of cerebral blood flow impaired in long-term Type I diabetic patients with clinical microangiopathy compared to healthy controls?
Population
12 long-term Type I diabetic patients with clinical microangiopathy and 9 healthy control subjects.
Comparison
Intravenous infusion of angiotensin amide II to… vs Healthy control subjects undergoing the same…
Design
Case-control
Authors
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Impaired cerebral autoregulation may heighten BP vulnerability in Type 1 diabetes with microangiopathy; leaves open whether modified targets are warranted.
Is autoregulation of cerebral blood flow impaired in long-term Type I diabetic patients with clinical microangiopathy compared to healthy controls?
Long-term Type I diabetic patients with microangiopathy demonstrate impaired cerebral blood flow autoregulation in response to acute blood pressure changes.
Kastrup et al. (1986) studied this question.
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