Why the study?
Does 10 weeks of improved metabolic control improve impaired autoregulation of subcutaneous blood flow in long-term insulin-dependent diabetic patients with clinical microangiopathy?
Population
8 long-term insulin-dependent diabetic patients with clinical microangiopathy
Comparison
10 weeks of improved metabolic control using… vs Baseline poor metabolic control
Design
Cohort
Follow-up
10 weeks
Authors
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Short-term metabolic improvement does not restore autoregulation in diabetic microangiopathy; leaves open whether longer control or adjunctive therapies alter microvascular function.
Does 10 weeks of improved metabolic control improve impaired autoregulation of subcutaneous blood flow in long-term insulin-dependent diabetic patients with clinical microangiopathy?
Ten weeks of strict metabolic control does not reverse impaired subcutaneous blood flow autoregulation in patients with long-term insulin-dependent diabetes and microangiopathy.
Kastrup et al. (1987) studied this question.
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