Population
Human tumor cells of astrocytic origin (glioma cells) and patient biopsies
Design
Preclinical
Authors
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Distinguishes glioma K+ channel profile from other cancers in animal models; leaves open human translation and therapeutic targeting.
Human glioma cells exclusively express functional BK-type calcium-activated potassium channels, which is distinct from other cancers that primarily express IK channels.
Weaver et al. (2006) studied this question.
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