This case report details the implantation of a total artificial heart in a human patient who survived for 112 days, highlighting operative, postoperative, and psychiatric considerations.
Does not support routine clinical adoption; leaves open the need for prospective trials on psychiatric management and durability.
This report details the implantation of a total artificial heart into a human being who survived for 112 days. Included are the criteria for candidate selection, the preoperative psychiatric evaluation, and the description of operative and postoperative complications in the context of the research subject's mental status over the period of his survival. Postmortem pathologic findings are reviewed. We summarize pertinent literature, including disordered behavior, postcardiotomy, and neuropsychiatric syndromes in hepatic, renal, and cardiac transplant patients.
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Claudia K. Berenson (1984) studied this question.
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