Why the study?
Does an unfractionated heparin dosage protocol based on sex, age, height, and weight improve the achievement of target antifactor Xa levels compared to a weight-based protocol in adult patients?
Population
569 adult patients receiving unfractionated heparin for eight different indications at a tertiary care…
Comparison
Unfractionated heparin dosage protocol based on… vs Weight-based unfractionated heparin dosage…
Design
Case_series
Follow-up
24 hours
Authors
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May support protocol refinement; leaves open superiority over weight-based dosing in randomized trials.
Does an unfractionated heparin dosage protocol based on sex, age, height, and weight improve the achievement of target antifactor Xa levels compared to a weight-based protocol in adult patients?
A computerized unfractionated heparin dosing protocol incorporating sex, age, height, and weight improves the achievement of target antifactor Xa levels within 24 hours compared to a weight-only protocol.
Rosborough et al. (2004) studied this question.
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