Why the study?
Does salt intake correlate with the degree of hypertensive target organ disease?
Population
Patients with essential hypertension and potential target organ disease
Design
Review
Authors
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Supports sodium reduction for LVH regression in hypertension; hypothesis-generating and requires RCTs to confirm outcomes beyond BP effects.
Does salt intake correlate with the degree of hypertensive target organ disease?
Dietary sodium intake correlates closely with hypertensive target organ disease, suggesting it is a direct perpetrator of cardiovascular disease independent of blood pressure fluctuations.
F H Messerli (1997) studied this question.
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