May 1, 1990Journal of Applied Physiology

Factors affecting whole blood O2 transfer kinetics: implications for theta(O2)

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Population

Thin layers of whole blood (WB)

Design

Preclinical

Authors

EHE. HeidelbergerUniversity at Buffalo, State University of New York RRRobert B. ReevesSimon Fraser University

Discussion

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Implication

Theta(O2) estimates require standardized conditions; leaves open a unique saturation relationship for oxygen transport modeling.

Structured PICO

Population

Thin layers of whole blood (WB)

Intervention

Varying experimental conditions including film thickness (1-6 microns), initial onloading PO2 gradient, and whole blood O2 affinity (P50)

Outcome

Half times (t0.5) of O2 uptake (on) and release (off), and specific O2 conductance [theta(O2)]surrogate

The study demonstrates that specific O2 conductance in whole blood is highly dependent on experimental conditions, challenging the assumption of a unique relationship with oxygen saturation.

Cite This Study

Heidelberger et al. (1990) studied this question.

synapsesocial.com/papers/6a6feb546ceb2bbd16dfc0d5 https://doi.org/10.1152/jappl.1990.68.5.1865

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Factors affecting whole blood O2 transfer kinetics: implications for theta(O2)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Factors affecting whole blood O2 transfer kinetics: implications for theta(O2)

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider