Why the study?
Does nicorandil affect the membrane currents and potential in rabbit sino-atrial node cells?
Does nicorandil affect the membrane currents and potential in rabbit sino-atrial node cells?
Nicorandil concentration-dependently decreases heart rate in rabbit sino-atrial node cells by selectively altering the conductance of the outward current.
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Highlights nicorandil's ion channel effects in rabbit SA node; leaves open translation to human electrophysiology.
Satoh et al. (1984) studied this question.
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