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October 14, 2005Journal of Applied Physiology

Portal vein cross-sectional area and flow and orthostatic tolerance: a 90-day bed rest study.

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Why the study?

Does flywheel exercise countermeasure affect portal vein cross-sectional area and orthostatic intolerance in subjects undergoing 90-day head-down tilt bed rest?

Population

18 subjects undergoing a 90-day head-down tilt (HDT) bed rest at 6 degrees

Comparison

Flywheel exercise countermeasures (CM) vs Controls (Con) without exercise countermeasures

Design

Other

Follow-up

90 days

Authors

PAPhilippe ArbeilleUniversité de ToursSBStephane S BesnardPKP. KerbeciCentre Hospitalier Universitaire de Tours

Discussion

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Implication

Flywheel exercise attenuates splanchnic distention during prolonged bed rest but does not prevent orthostatic intolerance; leaves open vasoconstriction mechanisms for prospective study.

Structured PICO

Does flywheel exercise countermeasure affect portal vein cross-sectional area and orthostatic intolerance in subjects undergoing 90-day head-down tilt bed rest?

P
Population
18 subjects undergoing a 90-day head-down tilt (HDT) bed rest at 6 degrees
I
Intervention
Flywheel exercise countermeasures (CM)
C
Comparator
Controls (Con) without exercise countermeasures
O
Outcome
Changes in portal vein cross-sectional area (PV CSA) and flow during a stand testsurrogate

Flywheel exercise countermeasures during 90-day bed rest reduced splanchnic network distention at rest but did not prevent orthostatic intolerance, which appears related to lower splanchnic arterial vasoconstriction.

Cite This Study

Arbeille et al. (2005) studied this question.

synapsesocial.com/papers/6a6ff3b4febe604dd708c4adhttps://doi.org/10.1152/japplphysiol.00331.2005
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