Why the study?
Do repeated lower body negative pressure and head-up tilt elicit different volume regulating hormone responses in healthy males?
Population
23 healthy males
Comparison
Three sequential 30-min bouts of lower body… vs Baseline and comparison between LBNP and HUT…
Design
Other
Follow-up
Up to 60 minutes after the 3rd stimulus
Authors
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Does not warrant changes in clinical hypovolemia assessment; leaves open whether LBNP-HUT differences persist in disease.
Do repeated lower body negative pressure and head-up tilt elicit different volume regulating hormone responses in healthy males?
Repeated central hypovolemia induced by LBNP and HUT elicits divergent hormonal responses, with repeated stress progressively increasing plasma aldosterone levels.
Roessler et al. (2011) studied this question.
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