What question did this study set out to answer?

To evaluate the impact of direct percutaneous coronary intervention on short-term hospital survival and one-year survival in patients presenting with acute STEMI following out-of-hospital cardiac arrest.

July 10, 2007Cardiology

Out-of-Hospital Cardiac Arrests in Patients with Acute ST Elevation Myocardial Infarctions in the East Bohemian Region over the Period 2002–2004

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Why the study?

Does direct PCI improve short-term and 1-year survival in patients with acute STEMI after out-of-hospital cardiac arrest?

Population

26 hospitalized individuals from the East Bohemian region with out-of-hospital cardiac arrest and acute ST…

Comparison

Urgent coronary angiography and direct… vs No urgent coronary angiography or reperfusion…

Design

Cohort

Follow-up

1 year

Authors

MPM PleskotUniversity of Colorado Hospital ABAnush BabuUniversity of Colorado Hospital RHRadka HazukováUniversity Hospital Olomouc

Discussion

Member takes

Implication

Direct PCI was associated with higher short-term survival; hypothesis-generating and requires randomized confirmation before changing practice.

Key Points

To evaluate the impact of direct percutaneous coronary intervention on short-term hospital survival and one-year survival in patients presenting with acute STEMI following out-of-hospital cardiac arrest.
Prospective study of 26 hospitalized patients (22 men, 4 women; aged 35–79 years, median 58.5) with STEMI after out-of-hospital cardiac arrest enrolled between April 2002 and August 2004.
Urgent coronary angiography was performed in 20 patients and direct percutaneous coronary intervention (PCI) in 19 patients, while 6 patients did not undergo angiography.
Tracked acute in-hospital survival, neurological status at discharge, coronary angiographic characteristics, and post-discharge mortality at 1-year follow-up.
In-hospital survival was 68.4% (13/19) in the direct PCI group and 70.0% (14/20) in the urgent angiography group, compared to 16.7% (1/6) among patients without angiography.
Overall hospital survival was 57.7% (15/26), with 11 patients discharged without neurological deficits.
Following PCI, optimal angiographic reperfusion (TIMI flow grade II–III) was achieved in 17 patients, and 0 deaths occurred during the 1-year follow-up among discharged survivors.

Structured PICO

Does direct PCI improve short-term and 1-year survival in patients with acute STEMI after out-of-hospital cardiac arrest?

Population

26 hospitalized individuals (22 men, 4 women, aged 35-79 years, median 58.5) from the East Bohemian region with out-of-hospital cardiac arrest (OHCA) and acute ST segment elevation myocardial infarction (STEMI).

Intervention

Urgent coronary angiography and direct percutaneous coronary intervention (PCI).

Comparator

No urgent coronary angiography or reperfusion therapy.

Outcome

Short-term survival (discharge from acute hospitalization) and 1-year survival.hard clinical

Direct PCI in patients with acute STEMI complicated by out-of-hospital cardiac arrest is associated with high rates of short-term survival and excellent 1-year outcomes.

Cite This Study

Pleskot et al. (2007) studied this question.

synapsesocial.com/papers/6a6ff5ad26a7f98052dc81bf https://doi.org/10.1159/000105325

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Implication

Direct PCI was associated with higher short-term survival; hypothesis-generating and requires randomized confirmation before changing practice.

Out-of-Hospital Cardiac Arrests in Patients with Acute ST Elevation Myocardial Infarctions in the East Bohemian Region over the Period 2002–2004

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

Out-of-Hospital Cardiac Arrests in Patients with Acute ST Elevation Myocardial Infarctions in the East Bohemian Region over the Period 2002–2004

Discussion

Member takes

Implication

Key Points

Structured PICO

Cite This Study

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