Key result
ICU stay >5 days linked to ~10-fold higher in-hospital mortality in STEMI with resuscitated OHCA.
Why the study?
In patients with OHCA complicating STEMI who are successfully resuscitated and treated with primary PCI, clinical and angiographic predictors of in-hospital mortality remain to be determined.
Population
78 patients with STEMI and OHCA successfully resuscitated and treated with primary PCI
Comparison
Survivors vs non-survivors
Design
Cohort study
Follow-up
In-hospital
Authors
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Prolonged ICU stay flags high mortality risk in STEMI-OHCA; hypothesis-generating and should not yet change practice.
Cohort (n=78)
No
Odds Ratio: 9.96 (95% CI 2.81–35.25)
p-value: p=0.0002
In patients with STEMI and resuscitated OHCA undergoing primary PCI, prolonged ICU stay, mechanical ventilation >48 hours, renal failure, anaemia, cardiogenic shock, and multivessel disease are strong independent predictors of in-hospital mortality.
Bărcan et al. (2016) conducted a cohort in ST-Segment Elevation Acute Myocardial Infarction and Resuscitated Out-Of-Hospital Cardiac Arrest (n=78). Duration of stay in ICU > 5 days vs. Duration of stay in ICU ≤ 5 days was evaluated on In-hospital mortality (OR 9.96, 95% CI 2.81-35.25, p=0.0002). In patients with STEMI and resuscitated out-of-hospital cardiac arrest, a duration of stay in the ICU longer than 5 days was the strongest independent predictor of in-hospital mortality (OR 9.96).
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