Key result
OHCA in STEMI patients is linked to ~150% higher mortality beyond 30 days.
Why the study?
Data regarding long-term survival in patients presenting with STEMI and out of hospital cardiac arrest were limited.
Does out of hospital cardiac arrest worsen long-term survival in patients presenting with STEMI?
Population
3521 consecutive STEMI patients undergoing PPCI or coronary artery bypass surgery
Comparison
OHCA vs no cardiac arrest
Design
Prospective cohort study
Follow-up
Mean follow-up of 18.6 months
Authors
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Out-of-hospital cardiac arrest signals higher long-term STEMI mortality risk; hypothesis-generating for risk stratification and requires prospective validation.
Cohort (n=3,521)
Does out of hospital cardiac arrest worsen long-term survival in patients presenting with STEMI?
Hazard Ratio: 2.5 (95% CI 0.99–6.3)
Absolute Event Rate: 7.9% vs 3.8%
p-value: p=0.04
In patients with STEMI, out of hospital cardiac arrest is associated with significantly higher in-hospital and long-term all-cause and cardiac mortality.
Samanta et al. (2018) conducted a cohort in STEMI (n=3,521). Out of hospital cardiac arrest (OHCA) vs. No cardiac arrest was evaluated on Mortality beyond 30 days (HR 2.5, 95% CI 0.99-6.3, p=0.04). In patients with STEMI, out of hospital cardiac arrest was a significant predictor of mortality beyond 30 days compared to no cardiac arrest (7.9% vs 3.8%; HR 2.5, 95% CI 0.99-6.3; p=0.04).
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