Why the study?
Does postprandial lipaemia differ between men with familial combined hyperlipidaemia, familial hypercholesterolaemia, and healthy controls?
Population
83 men, including 34 with familial combined hyperlipidaemia, 29 with familial hypercholesterolaemia, and 20…
Comparison
Oral fat tolerance test vs Healthy men and comparisons between FCH and FH…
Design
Cross-sectional
Authors
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Exaggerated postprandial lipaemia may contribute to excess CV risk in FCH; hypothesis-generating and requires prospective validation before clinical adoption.
Does postprandial lipaemia differ between men with familial combined hyperlipidaemia, familial hypercholesterolaemia, and healthy controls?
Men with familial combined hyperlipidaemia and the FH IIB phenotype exhibit an exaggerated postprandial triglyceride response, potentially contributing to their high cardiovascular risk.
Pavlidis et al. (2010) studied this question.
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