Population
Cl channel derived from colonic enterocyte plasma membrane vesicles incorporated into planar lipid bilayer…
Design
Preclinical
Authors
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No immediate clinical implications; hypothesis-generating for a shared binding site in colonic Cl channels.
Similarities in electrostatic potential maps of these open-channel blockers suggest they may bind to a single shared binding site within the colonic Cl channel protein.
Singh et al. (1991) studied this question.
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