Why the study?
Does treatment to reduce blood pressure and reverse aortic stiffness improve survival in patients with end-stage renal disease?
Population
Patients with end-stage renal disease (ESRD)
Design
Review
Authors
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Hypothesis-generating for targeting aortic stiffness in ESRD; prospective trials needed before changing practice.
Does treatment to reduce blood pressure and reverse aortic stiffness improve survival in patients with end-stage renal disease?
Arterial stiffness and calcification are key drivers of cardiovascular mortality in ESRD, and targeting these factors through blood pressure reduction improves survival.
London et al. (2002) studied this question.
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