January 4, 2018Journal of Hypertension
Clinical relevance of aortic stiffness in end-stage renal disease and diabetes
Key result
Aortic stiffness, measured by carotid-femoral pulse wave velocity, is a significant predictor of cardiovascular risk in patients with diabetes or end-stage renal disease independently of BP control.
Why the study?
Does aortic stiffness predict cardiovascular risk in patients with end-stage renal disease and diabetes?
Population
Patients with end-stage renal disease (ESRD) and diabetes
Design
Review
Authors
Discussion
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Implication
May refine CV risk assessment beyond BP in diabetes and ESRD; hypothesis-generating without interventional outcome data.
Structured PICO
Does aortic stiffness predict cardiovascular risk in patients with end-stage renal disease and diabetes?
P
Population
Patients with end-stage renal disease (ESRD) and diabetes
I
Intervention
Measurement and monitoring of aortic stiffness (carotid-femoral pulse wave velocity, cf-PWV)
O
Outcome
Cardiovascular risk and eventssurrogate
Aortic stiffness, measured by cf-PWV, is an important independent predictor of cardiovascular risk in patients with ESRD and diabetes, and may serve as a target for preventive strategies.
Cite This Study
Yannoutsos et al. (2018) conducted a review in End-stage renal disease and diabetes. Carotid-femoral pulse wave velocity (cf-PWV) was evaluated. Aortic stiffness, measured by carotid-femoral pulse wave velocity, is a significant predictor of cardiovascular risk in patients with diabetes or end-stage renal disease independently of BP control.