Key result
PM2.5 exposure is linked to higher risk of CKD progression, ESKD, and mortality.
Why the study?
Cardiovascular disease is a major contributor to mortality in end-stage renal disease patients, and the impact of cardiovascular risk markers on outcomes in this population requires analysis.
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Supports integrating air quality into prognostic models for dialysis patients; leaves open whether mitigation alters progression or survival.
Guérin et al. (2006) conducted a review in Chronic kidney disease and end-stage renal disease. Air pollution exposure (e.g., PM2.5, NO2, O3) vs. Lower levels of air pollution exposure was evaluated. Exposure to air pollution, particularly fine particulate matter (PM2.5), is consistently associated with an increased risk of chronic kidney disease progression, end-stage kidney disease, and mortality among dialysis and transplant patients.
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