March 24, 2021Journal of the American Heart AssociationOpen Access

Significantly lower in-hospital mortality in the Midwest compared with the Northeast (HR 0.64; 95% CI 0.51–0.8; P <0.00001).

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Why the study?

Regional disparities in cardiovascular disease outcomes have been suggested across the United States, but whether significant regional differences exist in care quality and short-term outcomes among hospitalized heart failure patients remained to be examined.

Does US geographic region impact quality of care and short-term outcomes in patients hospitalized for heart failure?

Population

423 333 patients hospitalized for HF in 488 hospitals across 4 US Census Bureau regions

Comparison

Comparison across 4 US Census Bureau regions

Design

Registry-based observational study

Authors

LCLuke Cunningham GFGregg C. Fonarow CYClyde W. Yancy

Discussion

Member takes

Overview

Persistent regional HF care and outcome disparities warrant attention; leaves open whether targeted interventions can reduce gaps.

Structured PICO

Does US geographic region impact quality of care and short-term outcomes in patients hospitalized for heart failure?

Population

423,333 patients hospitalized for heart failure in 488 hospitals across 4 US Census Bureau regions, enrolled in the GWTG-HF (Get With The Guidelines–Heart Failure) registry from 2010 to 2016.

Intervention

Hospitalization in specific US Census Bureau regions (e.g., Midwest)

Comparator

Hospitalization in other US Census Bureau regions (e.g., Northeast)

Outcome

In-hospital mortality and length of stayhard clinical

Despite similar quality of care across US regions, risk-adjusted in-hospital mortality for heart failure is significantly lower in the Midwest compared to the Northeast.

Limitations

Unmeasured differences in patient characteristics

Cite This Study

Cunningham et al. (2021) studied this question.

synapsesocial.com/papers/6a7002c878a11c550e09cd1d https://doi.org/10.1161/jaha.120.018696

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March 24, 2021Journal of the American Heart AssociationOpen Access

Significantly lower in-hospital mortality in the Midwest compared with the Northeast (HR 0.64; 95% CI 0.51–0.8; P <0.00001).

View Full Paper

Ask AI

Bookmark

Why the study?

Does US geographic region impact quality of care and short-term outcomes in patients hospitalized for heart failure?

Population

423 333 patients hospitalized for HF in 488 hospitals across 4 US Census Bureau regions

Comparison

Comparison across 4 US Census Bureau regions

Design

Registry-based observational study

Authors

LCLuke Cunningham GFGregg C. Fonarow CYClyde W. Yancy

Discussion

Member takes

Overview

Persistent regional HF care and outcome disparities warrant attention; leaves open whether targeted interventions can reduce gaps.

Structured PICO

Does US geographic region impact quality of care and short-term outcomes in patients hospitalized for heart failure?

Population

423,333 patients hospitalized for heart failure in 488 hospitals across 4 US Census Bureau regions, enrolled in the GWTG-HF (Get With The Guidelines–Heart Failure) registry from 2010 to 2016.

Intervention

Hospitalization in specific US Census Bureau regions (e.g., Midwest)

Comparator

Hospitalization in other US Census Bureau regions (e.g., Northeast)

Outcome

In-hospital mortality and length of stayhard clinical

Despite similar quality of care across US regions, risk-adjusted in-hospital mortality for heart failure is significantly lower in the Midwest compared to the Northeast.

Limitations

Unmeasured differences in patient characteristics

Cite This Study

Cunningham et al. (2021) studied this question.

synapsesocial.com/papers/6a7002c878a11c550e09cd1d https://doi.org/10.1161/jaha.120.018696

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

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