June 1, 1962Blood

Thrombotic State after a Hemorrhagic Diathesis, a Possible Complication of Therapy with Epsilon-Aminocaproic Acid

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Population

81-year-old man with disseminated carcinoma of the prostate and a hemorrhagic state with afibrinogenemia (n=1)

Design

Case_report

Authors

RNRichard L. NaeyeUniversity of Vermont

Discussion

Member takes

Implication

Potential thrombotic risk with epsilon-aminocaproic acid in hemorrhagic diathesis merits caution; case report leaves open systematic confirmation.

Structured PICO

Population

81-year-old man with disseminated carcinoma of the prostate and a hemorrhagic state with afibrinogenemia (n=1)

Intervention

Epsilon-aminocaproic acid and hydrocortisone

Outcome

Development of widespread intravascular thrombosessafety

Epsilon-aminocaproic acid may inhibit fibrinolysis and unmask intravascular coagulation, leading to widespread thromboses in patients with hemorrhagic diathesis.

Cite This Study

Richard L. Naeye (1962) studied this question.

synapsesocial.com/papers/6a7005f635aa2c282ce153a3 https://doi.org/10.1182/blood.v19.6.694.694

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Implication

Potential thrombotic risk with epsilon-aminocaproic acid in hemorrhagic diathesis merits caution; case report leaves open systematic confirmation.

Thrombotic State after a Hemorrhagic Diathesis, a Possible Complication of Therapy with Epsilon-Aminocaproic Acid

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Thrombotic State after a Hemorrhagic Diathesis, a Possible Complication of Therapy with Epsilon-Aminocaproic Acid

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider