Key result
Therapy with epsilon-aminocaproic acid rapidly normalized fibrinogen levels in a man with metastatic prostate cancer and DIC, whereas high-dose estrogen therapy failed to correct the coagulopathy.
Why the study?
Does epsilon-aminocaproic acid improve coagulopathy in a patient with metastatic prostate cancer and DIC?
Population
1 man with metastatic prostate cancer who developed disseminated intravascular coagulation and soft tissue…
Design
Case_report
Authors
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Epsilon-aminocaproic acid may normalize fibrinogen in refractory prostate cancer DIC; single case leaves open need for controlled studies.
Case Report (n=1)
Does epsilon-aminocaproic acid improve coagulopathy in a patient with metastatic prostate cancer and DIC?
Epsilon-aminocaproic acid successfully corrected coagulopathy in a patient with metastatic prostate cancer and DIC with excessive fibrinolysis.
Cooper et al. (1992) conducted a case report in Metastatic prostate cancer with disseminated intravascular coagulation and excessive fibrinolysis (n=1). Epsilon-aminocaproic acid vs. High-dose estrogen therapy (prior treatment) was evaluated on Fibrinogen levels and coagulopathy resolution. Therapy with epsilon-aminocaproic acid rapidly normalized fibrinogen levels in a man with metastatic prostate cancer and DIC, whereas high-dose estrogen therapy failed to correct the coagulopathy.
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