Population
frog neuromuscular junction and cultured rat myotubes
Design
Preclinical
Authors
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Does not guide clinical practice; leaves open extension of amine block to human cardiac channels.
Small organic amine compounds depress single channel conductance in acetylcholine receptors, with permeation well-described by a two-barrier Eyring model.
Sánchez et al. (1986) studied this question.
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