Population
Adult frog muscle fibres (endplates)
Design
Preclinical
Authors
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No immediate clinical implications; extends basic characterization of nicotinic channel block in animal models and leaves translation open.
This basic science study characterizes the ion channel blocking properties of nicotinic agonists at the frog neuromuscular junction, showing suberyldicholine is a more potent blocker than acetylcholine or carbachol.
Ogden et al. (1985) studied this question.
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