Why the study?
Does nortriptyline alter heart rate variability in panic disorder patients?
Population
13 panic disorder patients
Comparison
Nortriptyline vs Baseline (before treatment)
Design
Cohort
Authors
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May warrant HR monitoring during nortriptyline use in panic disorder; leaves open effects on cardiovascular outcomes.
Does nortriptyline alter heart rate variability in panic disorder patients?
Nortriptyline treatment in panic disorder patients is associated with increased heart rate and decreased mid-frequency power, suggesting decreased sympathetic activity alongside anticholinergic effects.
Yeragani et al. (2008) studied this question.
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