Why the study?
Does nortriptyline or paroxetine affect QT variability in patients with panic disorder?
Population
29 patients with panic disorder
Comparison
Nortriptyline (n=13) or paroxetine (n=16) vs Before treatment (baseline)
Design
Cohort
Authors
Loading...
Nortriptyline may increase QT variability in panic disorder; leaves open differential cardiac safety versus paroxetine, needs confirmation.
Does nortriptyline or paroxetine affect QT variability in patients with panic disorder?
Nortriptyline, but not paroxetine, increases QT variability in patients with panic disorder, suggesting paroxetine may be a safer choice for patients with coexisting cardiac disease.
Yeragani et al. (2000) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: