Why the study?
Does an enzyme-linked immunosorbent assay accurately detect rhinovirus antigens in clinical specimens compared to virus isolation?
Population
36 clinical specimens (nasal washings) and 57 different human rhinovirus serotypes
Comparison
Enzyme-linked immunosorbent assay for rhinovirus… vs Virus isolation
Design
Other
Authors
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CCA ELISA correlates better than direct ELISA with virus isolation; leaves open routine diagnostic adoption pending larger validation.
Does an enzyme-linked immunosorbent assay accurately detect rhinovirus antigens in clinical specimens compared to virus isolation?
A newly developed ELISA provides a sensitive method for detecting rhinovirus antigens in clinical specimens, showing good correlation with traditional virus isolation.
Dearden et al. (1987) studied this question.
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