Why the study?
Does a newly developed ELISA accurately detect rhinovirus antigens compared to virus isolation in volunteers inoculated with human rhinovirus?
Population
54 volunteers inoculated with 100 TCID50 of human rhinovirus type 2 (HRV-2)
Comparison
Newly developed enzyme-linked immunosorbent… vs Virus isolation
Design
Cohort
Follow-up
3 days
Authors
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ELISA may aid rhinovirus detection in research volunteers; leaves open validation and utility in clinical diagnosis.
Does a newly developed ELISA accurately detect rhinovirus antigens compared to virus isolation in volunteers inoculated with human rhinovirus?
A newly developed ELISA is a simple, rapid, and sensitive alternative to virus isolation for diagnosing rhinovirus infection.
Al‐Nakib et al. (1989) studied this question.
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