September 6, 2011European Journal of Echocardiography

Feasibility of detecting early left ventricular systolic dysfunction using global area strain: a novel index derived from three-dimensional speckle-tracking echocardiography

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Why the study?

Does global area strain derived from 3D-STE improve the detection of early left ventricular systolic dysfunction compared to conventional strain parameters in patients at risk for heart failure?

Population

160 subjects with or without heart failure

Comparison

Global area strain measurement using… vs Conventional echocardiographic parameters…

Design

Cross-sectional

Authors

HWHeling WenUniversity of Electronic Science and Technology of China ZLZichang LiangBeibu Gulf University YZYongfeng ZhaoCentral South University

Discussion

Member takes

Implication

Global area strain from 3D-STE may aid early LV dysfunction detection in at-risk patients; leaves open its added prognostic value versus conventional parameters in prospective cohorts.

Structured PICO

Does global area strain derived from 3D-STE improve the detection of early left ventricular systolic dysfunction compared to conventional strain parameters in patients at risk for heart failure?

Population

160 subjects with or without heart failure (137 analyzed with reliable tracking quality: 30 healthy volunteers, 29 Stage A HF, 37 Stage B HF, 26 Stage C HF, and 15 Stage D HF)

Intervention

Global area strain (AS) measurement using three-dimensional speckle-tracking echocardiography (3D-STE)

Comparator

Conventional echocardiographic parameters including global longitudinal strain (LS), circumferential strain (CS), radial strain (RS), and left ventricular ejection fraction (LVEF)

Outcome

Detection of early left ventricular systolic dysfunction (ability to differentiate normal controls from patients with Stage A HF)surrogate

Global area strain derived from 3D-STE is a sensitive parameter for detecting early, subtle left ventricular systolic dysfunction in patients at risk for heart failure, outperforming conventional strain measures.

Cite This Study

Wen et al. (2011) studied this question.

synapsesocial.com/papers/6a70106bb27f158178272e83 https://doi.org/10.1093/ejechocard/jer162

Topics

Heart failure HFrEF treatment

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Implication

Global area strain from 3D-STE may aid early LV dysfunction detection in at-risk patients; leaves open its added prognostic value versus conventional parameters in prospective cohorts.

Feasibility of detecting early left ventricular systolic dysfunction using global area strain: a novel index derived from three-dimensional speckle-tracking echocardiography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

Feasibility of detecting early left ventricular systolic dysfunction using global area strain: a novel index derived from three-dimensional speckle-tracking echocardiography

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider