Why the study?
Do growth hormone-deficient adults have altered levels of cardiovascular risk markers such as PAI-1 activity and fibrinogen compared to healthy controls?
Do growth hormone-deficient adults have altered levels of cardiovascular risk markers such as PAI-1 activity and fibrinogen compared to healthy controls?
Growth hormone-deficient adults exhibit elevated PAI-1 activity and fibrinogen levels, which may contribute to their increased atherothrombotic propensity and cardiovascular risk.
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May heighten thrombotic risk awareness in GH deficiency; leaves open causal role and therapy effects.
Johansson et al. (1994) studied this question.
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