Why the study?
Does insulin injection alter the morphometric characteristics of capillary endothelial cells in diabetic rats?
Population
Diabetic rats
Comparison
Insulin injection vs Diabetic and nondiabetic rats injected with saline
Design
Preclinical
Follow-up
1 hour
Authors
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May modulate endothelial vesicular transport in diabetic rats; leaves open human microvascular relevance.
Does insulin injection alter the morphometric characteristics of capillary endothelial cells in diabetic rats?
Insulin acutely alters the kinetics of the vesicular transport pathway in the capillary endothelium of diabetic rats, which may explain clinical decreases in plasma volume and intravascular albumin.
Østerby et al. (1978) studied this question.
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