Synapse
⌘+K
Synapse
PulseExploreJournal ClubResearchersJournals
Instagram
HomeJournal ClubExplore
January 1, 2010Thrombosis and Haemostasis

High on-treatment platelet reactivity by more than one agonist predicts 12-month follow-up cardiovascular death and non-fatal myocardial infarction in acute coronary syndrome patients receiving coronary stenting

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Does high on-treatment platelet reactivity to more than one agonist predict cardiovascular death and non-fatal MI in ACS patients undergoing PCI with stenting?

Population

1,108 acute coronary syndrome patients undergoing percutaneous coronary intervention with stent implantation

Comparison

High on-treatment platelet reactivity to more… vs Isolated platelet hyperreactivity to only one…

Design

Cohort

Follow-up

12 months

Authors

AGAnna Maria GoriRPRita PanicciaBGBetti Giusti

Discussion

Loading...

Member takes

Overview

May aid post-PCI risk stratification in ACS; hypothesis-generating and should not yet change practice.

Structured PICO

Does high on-treatment platelet reactivity to more than one agonist predict cardiovascular death and non-fatal MI in ACS patients undergoing PCI with stenting?

P
Population
1,108 acute coronary syndrome patients undergoing percutaneous coronary intervention (PCI) with stent implantation
I
Intervention
High on-treatment platelet reactivity to more than one agonist (ADP, arachidonic acid, collagen) measured by light transmission aggregometry
C
Comparator
Isolated platelet hyperreactivity to only one agonist or no hyperreactivity
O
Outcome
Cardiovascular death and non-fatal myocardial infarction at 12-month follow-uphard clinical

High on-treatment platelet reactivity to multiple agonists (ADP, AA, collagen) is an independent predictor of 12-month cardiovascular death and non-fatal MI in ACS patients undergoing PCI.

Cite This Study

Gori et al. (2010) studied this question.

synapsesocial.com/papers/6a701f2efe4101aa97e00587https://doi.org/10.1160/th10-01-0007
View Full Paper
Ask AI
Bookmark
Share