Population
Patients with acute and chronic cardiovascular indications, including pulmonary arterial hypertension…
Design
Review
Authors
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Endothelin antagonists should not be added in heart failure; confirms lack of benefit while leaving open further study in hypertension.
Endothelin receptor antagonists are effective in pulmonary arterial hypertension but have failed to show benefit in heart failure, with ongoing research in other cardiovascular indications.
Kirchengast et al. (2005) studied this question.
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