Key result
Prior stroke linked to ~33% slower choice reaction time and poorer cognition in older adults.
Case-Control (n=180)
Answers are grounded in this paper and cite their sources.
BACKGROUND: Few studies have examined the profile of cognitive impairments in older stroke patients without dementia. METHOD: A standardized evaluation including a detailed neuropsychological assessment [Cambridge Examination for Mental Disorders in the Elderly--cognitive subscale (CAMCOG)] and computerised tests of attention and working memory from the Cognitive Drug Research battery were undertaken in 150 stroke survivors of >75 years of age and 30 elderly controls. RESULTS: The stroke survivors without dementia had significantly greater overall impairment on the CAMCOG, as well as significantly greater impairment in memory, simple reaction time, choice reaction time (CRT), vigilance accuracy, CRT variability, spatial working memory reaction time (SWMRT) and numerical working memory than the elderly controls (e.g. CRT [up] 33%, SWMRT [up] 61%, memory [down] 11%). CONCLUSION: Impairments of cognitive processing speed, working memory and executive functions are frequent in elderly stroke patients without dementia and represent the main cognitive components of early cognitive impairments.
No takes yet. Share an insight, caveat, or question.
Ballard et al. (2003) conducted a case-control in Stroke without dementia (n=180). Prior stroke vs. Elderly controls was evaluated on Overall impairment on the CAMCOG and computerized tests of attention and working memory. Prior stroke in older patients without dementia was associated with significantly greater cognitive impairment, including a 33% increase in choice reaction time and 11% decrease in memory vs controls.
Synapse has enriched 10 related papers. Consider them for comparative context: