Why the study?
Does percutaneous PFO closure prevent secondary embolic events in patients with PFO and prior stroke?
Does percutaneous PFO closure prevent secondary embolic events in patients with PFO and prior stroke?
Percutaneous PFO closure is a minimally invasive procedure with high success and low morbidity that may be considered for secondary prevention of embolic events.
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PFO stroke risk and closure benefit remain controversial; leaves open optimal patient selection for screening and intervention.
Stroke is the most debilitating cardiovascular event. It has a variety of causes that may be present simultaneously. In young or otherwise healthy people a patent foramen ovale (PFO) is increasingly searched for. In stroke of the elderly atherosclerosis and atrial fi brillation are in the foreground but the PFO should not be ignored. The risk of a PFO related stroke over time is controversial and so is its prevention by PFO closure. Percutaneous PFO closure is a minimally invasive procedure which can be performed with high success and low morbidity. We review the rationale for PFO closure for secondary prevention of embolic events.
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Wahl et al. (2017) studied this question.
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